These are mechanics you wanted to crop up everywhere, so write them down!
Some variant of progressing in stages and gradually suffering worse effects (and possibly having an easier or harder time recovering). Will involve many tables.
Disease will be a two-way journey (get worse, get better). Poisons will be one-way (you just get worse, but when the poison has run its course you heal naturally).
These are mechanics you wanted to crop up everywhere, so write them down!
Some variant of progressing in stages and gradually suffering worse effects (and possibly having an easier or harder time recovering). Will involve many tables.
Disease will be a two-way journey (get worse, get better). Poisons will be one-way (you just get worse, but when the poison has run its course you heal naturally).