Save settings in Mutltisite Install resulting in page not found

*** YOU MUST ANSWER ALL QUESTIONS. IF A QUESTION IS NOT RELEVANT YOU MUST
WRITE "NOT APPLICABLE" IN THE QUESTION FIELD. ***

[What steps will reproduce the problem? (We need detailed, specific steps.
If we cannot reproduce the defect on a dev machine, we cannot fix it.)]
1.In Multisite Admin i try and change the settings (I don't want users to 
upload audio / video)
2.I press save settings
3. It tries to find www.mydomain.com/wp-admin/network/options.php but gives me 
a 404.

This happens both from the network admin and from the website admin. This is my 
main site and I haven't network activated the post as only this site has 
buddypress.

[What is the expected output? What do you see instead?]
I don't know, probably some sort of success message.

[What version of BP Media are you using?]
2.2.5

[What version of WordPress are you using?]
3.4.2

[What version of BuddyPress are you using?]
1.6.1

[What version of PHP are you using?]
5.5?

[If the problem is layout related (broken page layout, etc) or browser
related (page just freezes, cannot connect to server) ...what happens when
you load the page in AT LEAST TWO of the following browsers:]
1.FireFox - (Report version number)
2.Internet Explorer - (Report version number)
3.Safari - (Report version number)
4.Google Chrome - (Report version number)
Not applicable

[What is the URL of your web host?]

[If you are running a public site, what is the URL to a page that shows the
problem?]
the site is www.mudandroutes.com - but problem is only apparent in admin.

[Do you know how to use phpMyAdmin?]
yes

[Do you know how to edit PHP code?]
yes - if given the code!

[Please provide any additional information below]
Thanks.

Original issue reported on code.google.com by walker...@gmail.com on 11 Nov 2012 at 5:29

joeey1984ad / buddypress-media

Save settings in Mutltisite Install resulting in page not found #104