search

jon-xu / scSplit

Genotype-free demultiplexing of pooled single-cell RNA-Seq, using a hidden state model for identifying genetically distinct samples within a mixed population.
MIT License
39 stars 9 forks source link

Possibility to use for sc/snATAC-seq? #12

Closed HaglundA closed 3 years ago

HaglundA commented 3 years ago

Hi,

I hope this finds you well. Not an issue per se, but I was wondering whether you had explored or considered the use of scSplit for demultiplexing pooled samples in scATAC-seq (or snATAC-seq), specifically 10X data?

Thanks!

jon-xu commented 3 years ago

Hi, Thanks for the question - it's an interesting idea! Unfortunately we didn't test this tool on sc/snATAC-seq yet, although theoretically it should be possible. Cheers