Notes:
Before starting the process of rotation, it is important to know how many chromosomes are present in the genome (some bacterial genomes can have more than one chromosome and close in size to a plasmid). A genome is considered "closed" only when all chromosomes are complete and circular (plasmids need not be complete).
Notes: Before starting the process of rotation, it is important to know how many chromosomes are present in the genome (some bacterial genomes can have more than one chromosome and close in size to a plasmid). A genome is considered "closed" only when all chromosomes are complete and circular (plasmids need not be complete).