issues
search
jr-leary7
/
scLANE
Characterize gene dynamics over trajectories using GLMs, GEEs, & GLMMs.
MIT License
7
stars
2
forks
source link
Add function to test significance of gene program score across trajectory
#183
Closed
jr-leary7
closed
6 months ago
jr-leary7
commented
6 months ago
Normalize scores to (0, 1) -- NOT [0, 1]
Fit Beta distribution GAM with pseudotime as covariate and compare to null model with Wald test
Return test statistic,
p
-value, etc.