Open DarwinAwardWinner opened 6 years ago
Here is my session info, although I have also observed this on another machine running R 3.4.4:
> sessionInfo()
R version 3.5.0 (2018-04-23)
Platform: x86_64-apple-darwin17.5.0 (64-bit)
Running under: macOS High Sierra 10.13.4
Matrix products: default
BLAS: /System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/libBLAS.dylib
LAPACK: /System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/libLAPACK.dylib
locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8
attached base packages:
[1] grDevices datasets parallel graphics stats4 stats utils
[8] methods base
other attached packages:
[1] sva_3.28.0 BiocParallel_1.14.1 genefilter_1.62.0
[4] mgcv_1.8-23 nlme_3.1-137 BiocInstaller_1.30.0
[7] tidyr_0.8.0 devtools_1.13.5 openxlsx_4.0.17
[10] magrittr_1.5 dplyr_0.7.4 foreach_1.4.4
[13] plyr_1.8.4 glue_1.2.0 stringr_1.3.1
[16] GenomicRanges_1.32.2 GenomeInfoDb_1.16.0 IRanges_2.14.8
[19] ggplot2_2.2.1 S4Vectors_0.18.1 BiocGenerics_0.26.0
loaded via a namespace (and not attached):
[1] purrr_0.2.4 splines_3.5.0 lattice_0.20-35
[4] colorspace_1.3-2 blob_1.1.1 XML_3.98-1.11
[7] survival_2.42-3 rlang_0.2.0 pillar_1.2.2
[10] withr_2.1.2 DBI_1.0.0 bit64_0.9-7
[13] bindrcpp_0.2.2 matrixStats_0.53.1 GenomeInfoDbData_1.1.0
[16] bindr_0.1.1 zlibbioc_1.26.0 munsell_0.4.3
[19] gtable_0.2.0 codetools_0.2-15 memoise_1.1.0
[22] Biobase_2.40.0 AnnotationDbi_1.42.1 Rcpp_0.12.16
[25] xtable_1.8-2 scales_0.5.0 limma_3.36.1
[28] annotate_1.58.0 XVector_0.20.0 bit_1.1-12
[31] digest_0.6.15 stringi_1.2.2 grid_3.5.0
[34] tools_3.5.0 bitops_1.0-6 lazyeval_0.2.1
[37] RCurl_1.95-4.10 tibble_1.4.2 RSQLite_2.1.1
[40] pkgconfig_2.0.1 Matrix_1.2-14 assertthat_0.2.0
[43] iterators_1.0.9 R6_2.2.2 compiler_3.5.0
For what it's worth, I think that NaN is probably the technically correct p-value for an F-test on a zero-variance row. But other functions that use f.pvalue
such as sva should also be modified to handle NaN p-values (most likely by just throwing away those genes).
I would expect the following to return all 1s, since each row is constant:
However, the result I get is:
This can cause problems and errors when running functions the use
f.pvalue
, such assva
.