jts / nanopolish

Signal-level algorithms for MinION data
MIT License
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nanopolish with fastq #1130

Closed mocherry closed 8 months ago

mocherry commented 8 months ago

Dear all,

I have fast5-files and a fastq-file from basecalling with Dorado. When I run: nanopolish index -d fast5_files/ reads.fastq I get the following error: error: could not open reads.fastq for read

As I do not have a sequencing summary file, I do not know how to do the indexing. On Github it says: "Without this option, nanopolish index is extremely slow as it needs to read every fast5 file individually"

but not that it does not work at all. I would have gone with the "extremely slow", but now I am at a loss.

Help would be appreciated. Thanks and best, Matthias