Closed sunhaifeng123 closed 1 year ago
Hi Haifeng,
It depends on the reason for merging these sequences. Are these sequences share similar functions? Some previous works (e.g., PMID: 23063653) have shown that some miRNAs with different length, although sharing the overlapping sequences, have distinct seed sequences and target specificity. Hope the information helps.
I have to close the issue since it's not related to the software.
Best, Junchao
Hi, Junchao,
I got the results from sports1.1, some similar sequences like:
AAAAAACATTAGACTGTGAATCTGACAACAGGAAATAAACCTCCT 42 30 232 53 296 24 46 104 197 229 AAAAAACATTAGACTGTGAATCTGACAACAGGAAATAAACCTCC 16 9 63 22 120 12 16 20 48 30 AAAAAACATTAGACTGTGAATCTGACAACAGGAAATAAACCTC 29 3 41 22 47 7 4 0 21 21
and my supervisor hope that I can merge such three sequence to one so that perfrom following differential analysis.
I don't know whether it's suitable here for smallRNA data process and I didn't find literatures with such a description.
Can you give me some ideas or suggestions?
Thank you very much in advance!
Best, Haifeng Sun
Ph.D. candidata student from Nanjing Medical University, China