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jyaacoub / MutDTA

Improving the precision oncology pipeline by providing binding affinity purtubations predictions on a pirori identified cancer driver genes.
https://drive.google.com/drive/folders/1mdiA1gf1IjPZNhk79I2cYUu6pwcH0OTD
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Improve PSSM feature #4

Closed jyaacoub closed 1 year ago

jyaacoub commented 1 year ago

Instead of using a probability distribution created from the MSA position frequency matrix, we can use Shannon entropy to give the model a better idea of what amino acids are essential to the structure.

jyaacoub commented 1 year ago

This has been addressed in 2de9777843ff211cbd5b14149655c47023238d64