kdahlquist / GRNmap

Gene Regulatory Network modeling and parameter estimation
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Bar Chart Analysis of Model Runs for 5, "15"-Gene Networks #274

Closed bklein7 closed 7 years ago

bklein7 commented 7 years ago

Bar charts will be used to assess modeling results generated in #265 per the guidelines specified during the Data Analysis Team meeting on Monday, November 7th:

  1. Make two separate bar charts showing production_rate & threshold_b values generated for each transcription factor, clustered to show the results from all 5 networks (do not include dCIN5 results until @kdahlquist updates this network).

  2. Make a bar chart showing the MSE values for each gene within the individual networks, clustered to show the different MSE values computed for each strain present within the network model.

bklein7 commented 7 years ago

Moving forward, we will consider coding a function in MATLAB to produce these graphs as part of GRNmap. However, we will focus on producing these results in Excel for now to expedite this process.

bklein7 commented 7 years ago

I created all requested bar charts and uploaded a PowerPoint presentation containing the results here.

kdahlquist commented 7 years ago
bklein7 commented 7 years ago

The bar chart analysis PowerPoint Presentation was updated to reflect the changes requested above. Specifically, threshold_b values for genes with no inputs (ABF1, GCR2, ZAP1) were adjusted to zero, and the language used in the chart legends was corrected.

I attempted to add the results from @Nwilli31's CIN5 model runs but could not find these output sheets posted in the Dahlquist Lab repository. Are they uploaded? And if so, should I include the data from both the 14 and 17 gene CIN5 networks?

kdahlquist commented 7 years ago

@Nwilli31 will need to respond about the location of the output sheets. When they are posted, please do the analysis for both networks.

Nwilli31 commented 7 years ago

I've uploaded the documents to the Dahlquist Repository. I can do the analysis for the two networks. I created an Excel file with all the strains' optimized production rates and threshold b values because I did not see on compiled in the Dahlquist Repository. The newest powerpoint can be found in the repository.

bklein7 commented 7 years ago

I looked at @Nwilli31's updates to the bar chart analysis powerpoint and noticed some issues. Primarily, the corrections made to account for the erroneous threshold_b values (#289) were not carried forward in the new powerpoint. I presume this is because @Nwilli31 did not see my excel file with the bar chart data and made a new one (for reference, this file is in the 15-gene_networks_analysis folder in the Dahlquist Lab repository). I have corrected for this issue and made a few other changes to the powerpoint, which is available here.

kdahlquist commented 7 years ago

This is done, so closing.