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kdahlquist / GRNmap

Gene Regulatory Network modeling and parameter estimation
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Output Graph Analysis of Model Runs for 5, "15"-Gene Networks #275

Closed bklein7 closed 7 years ago

bklein7 commented 7 years ago

The transcription factor output estimation graphs generated in #265 will be further analyzed per the guidelines specified during the Data Analysis Team meeting on Monday, November 7th:

  1. Display within-strain ANOVA values for each transcription factor on their respective output estimation graphs.

  2. Determine if there is a trend between within-strain ANOVA values and goodness-of-fit for the transcription factor output estimations.

  3. Create graphics that display all 14-16 updated transcription factor output estimation graphs for each of the individual networks.

Nwilli31 commented 7 years ago

@kdahlquist is there a specific location (OWW or Github repository) to find the within-strain ANOVA values for each transcription factor? Or would I have to run through the statistical analysis protocol again?

kdahlquist commented 7 years ago

I'm posting the ANOVA results to a directory in the DahlquistLab repository here:

https://github.com/kdahlquist/DahlquistLab/tree/master/data/within-strain_ANOVA_results

kdahlquist commented 7 years ago

OK, results are posted for wt, dCIN5, dGLN3, dHAP4, dHMO1, dZAP1. Can't do dSWI4 because it only has 4 timepoints and the script is expecting 5. I'll need to talk to @bengfitzpatrick about that.

In these files the column "B&H comps" has the Benjamini and Hochberg corrected p value.

bklein7 commented 7 years ago

I compiled the within strain ANOVA B&H p-values for each of the 6 strains in the wild type network in an excel file. I then copied these values over into the testing results PowerPoint from #265 and posted this updated version of the presentation here. There are sheets for each of the 5 networks in the excel file if @Nwilli31 would like to continue working with this issue this week.

kdahlquist commented 7 years ago

Item 2 on list at top of this issue is now superseded by #315, so closing this one.