optimization suggestions list

[yuankunzhu]

Open this issue as an aggregation for optimization suggestions.

• [ ] Alignment #47
• [ ] Marking duplicates, BQSR, sorting
• [ ] Metrics
• [ ] Validate Gvcf

[bogdang989]

@yuankunzhu I would add above:

• [x] BAM Preprocessing #49
• [x] Marking duplicates, BQSR, sorting #50
• [x] HaplotypeCaller optimal RamMin parameter #51
• [x] Optimal AWS Instance Type(s) #52