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kieranrcampbell / ouija

Descriptive probabilistic marker gene approach to single-cell pseudotime inference
http://kieranrcampbell.github.io/ouija
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Find switch-like genes on existing pseudotime #5

Closed charliex210 closed 6 years ago

charliex210 commented 6 years ago

Hello, Can I fit the model and find the switch-like genes based on existing pseudotime defined by other methods? Thanks!

kieranrcampbell commented 6 years ago

Yes, we have a method called switchde for this.

R package - https://bioconductor.org/packages/release/bioc/html/switchde.html

Paper - https://academic.oup.com/bioinformatics/article/33/8/1241/2736366

Let me know if you have any more questions.