search

konradjk / exac_browser

Browser for ExAC consortium data
http://exac.broadinstitute.org
MIT License
106 stars 54 forks source link

Accessing ExAC constraint metrics through the REST API #346

Open ROCrooks opened 6 years ago

ROCrooks commented 6 years ago

Hello, is there a way of retrieving the constraint metrics table through the ExAC REST API? I'm particularly interested in the expected missense and synonymous variant frequencies for one of my projects but haven't found any way to do it in the documentation at http://exac.hms.harvard.edu/. If there was a way of retrieving the entire constraint metrics table for a gene I think that would be really useful for a lot of people. Thanks.

ROCrooks commented 6 years ago

Update: I have found this (http://mygene.info/blog/functional-gene-constraint-scores-from-exac-now-available-from-mygene-info), which appears to be a way of doing what I need to do. I'll leave it here as well in case it is useful for anyone else. Thanks.

nawatts commented 5 years ago

The code in this repository backs http://exac.broadinstitute.org.

http://exac.hms.harvard.edu is based on a fork of this repository (https://github.com/hms-dbmi/exac_browser) and is operated by a different group (https://avillach-lab.hms.harvard.edu/exome-aggregation-consortium-exac). Questions about http://exac.hms.harvard.edu/rest would have to be directed there.