MLR - change analysis to use gene expression as the dependent variable

kordk / torch-ecpg

(GPU accelerated) eCpG mapper

BSD 3-Clause "New" or "Revised" License

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MLR - change analysis to use gene expression as the dependent variable #16

Closed kordk closed 1 year ago

kordk commented 1 year ago

We would like to follow the analysis design used by the Kennedy study (PMID 29914364): "For all transcripts and CpGs in each study, we regressed log expression signals for one transcript on methylation β-values for a single CpG..."

So, the model would be:

Gx ~ Mt + co-variates

liamgd commented 1 year ago

Changed in f1d1df8.