Open marcelm opened 7 months ago
As discussed previously, we should try to switch to a 2-bit encoded reference to save memory. Any nucleotides that are not A, C, G, T would need to be mapped to a pseudo-randomly chosen nucleotide (as BWA does).
As discussed previously, we should try to switch to a 2-bit encoded reference to save memory. Any nucleotides that are not A, C, G, T would need to be mapped to a pseudo-randomly chosen nucleotide (as BWA does).