kschan0214 / sepia

Matlab GUI pipeline application for quantitative susceptibility mapping (QSM)
MIT License
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fieldmap and localfieldmap #61

Closed linsi25 closed 1 year ago

linsi25 commented 1 year ago

Hy,

I am new to QSM and I am using SEPIA for generating my first chi-maps. It looks quite great! Anyway, I have scrolled through out the documentation but I am not able to find how the fieldmap is generated after the phase unwrapping, could you help me? I have both brain and phantom images. The phantom is a cylinder (24 cm diameter) filled with water with 4 inserts (about 6 cm diameter) with different susceptibility values. While SEPIA seems to function properly on brain images, I have unsatisfactory results for the phantom: in particular the phantom’s localfieldmap appears quite flat (I have tried different algorithms but nothing works). Have you any ideas about why in this simpler geometry the algorithm fails? Is there any method to check the ‘goodness’ of the localfieldmap generated by the background removal step? Thank you very much for your attention.

kschan0214 commented 1 year ago

Hi,

The quality of the output fieldmap and local field map depends on several factors, including the methods being used and the signal mask. For details about how the fieldmap is generated, you can check the reference listed here https://sepia-documentation.readthedocs.io/en/latest/pages/References.html#phase-unwrapping for the methods that you choose.

I would need more information to understand why the background field removal algorithms don't work on the phantom data (It worked on my phantom data in the past). Would you mind providing the following information if possible:

I do not know any of the algorithms that provide the goodness of fit measure. One way to check the local field map output is to look at the removed background field. This can be done by subtracting the fieldmap from the local field map:

Background field = fieldmap - local field

In principle, the derived background field should not contain any identifiable structures of the inserts.