Closed SC-Duan closed 2 years ago
Hello! If you're not comfortable estimating theta and the DivTime for your species isn't previously known, it might be worth just using the original Beta 1 statistic. That way you don't need theta or the DivTime. if you do really want to use B2, then I would get regions of the genome that you think are neutrally evolving, and calculate Watterson's theta on them.
Thanks for your reply. I just want to test the B2 results and I request the source code from Achaz to calculate the theta and have not heard back yet. Are there some softs can do it? Thank you very much!
Hi, I'm trying to calculate B2 using Betascan. This needs the theta value as a parameter, and how should I calculate it based on vcf file or beta input file? if I set DivTime parameter, this also need the 4Neu in BALLET. Thank you!