Open ktmeaton opened 1 year ago
Clade: BA.5.3,CJ.1 Lineage: BQ.1.8*,BA.2* Lineage Confidence: 0.993,0.977
BA.5.3
CJ.1
BQ.1.8*
BA.2*
0.993
0.977
RBD Level: 6 RBD Substitutions: S:K444T,S:L452R,S:N460K,S:F486P,S:F490S,S:R493Q Immune Escape: 0.7621 ACE2 Binding: 0.8882
6
S:K444T
S:L452R
S:N460K
S:F486P
S:F490S
S:R493Q
0.7621
0.8882
Higher values indicate an increased capacity to evade antibodies.
TBD
Higher values indicate an increased capacity for viral entry into the host cell.
proposed1658 is successfully detected with the sc2rf mode for voc-2022 and voc-2023:
proposed1658
sc2rf
voc-2022
voc-2023
The second parent could be CJ.1 (BA.2.75.3*):
BA.2.75.3*
Or the second parent could be XBF :
XBF
And is less likely to be XBB:
Breakpoint 1: 22918:23018
22918:23018
resources/breakpoints.tsv
The genetic similarities between XBB, XBF, and CJ.1 are going to cause problems for identifying diagnostic mutations when I next update the sc2rf mutation frequencies. This will also impact #234.
Parents
Clade:
BA.5.3
,CJ.1
Lineage:BQ.1.8*
,BA.2*
Lineage Confidence:0.993
,0.977
Immunity
RBD Level:
6
RBD Substitutions:S:K444T
,S:L452R
,S:N460K
,S:F486P
,S:F490S
,S:R493Q
Immune Escape:0.7621
ACE2 Binding:0.8882
Immune Escape Ranking
TBD
ACE2 Binding Ranking
TBD
Alleles
proposed1658
is successfully detected with thesc2rf
mode forvoc-2022
andvoc-2023
:The second parent could be
CJ.1
(BA.2.75.3*
):Or the second parent could be
XBF
:And is less likely to be XBB:
Breakpoints
Breakpoint 1:
22918:23018
Tasks
resources/breakpoints.tsv
Updated