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ktrns / scrnaseq

Workflow for single-cell RNA-seq analysis using Seurat
MIT License
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Seurat FindAllMarkers uses natural log to calculate FC, we'd like to have log2 #51

Closed ktrns closed 4 years ago

ktrns commented 4 years ago

https://github.com/satijalab/seurat/issues/3346#issue-672668498

Posted a question to the Seurat GitHub. If Seurat indeed uses the natural log, we should re-calculate it to log2. Its more intuitive to understand.

At the moment, we use a log2-based threshold for FC, which would be a bug.