Modifications in non-tryptic data

kusterlab / prosit

Prosit offers high quality MS2 predicted spectra for any organism and protease as well as iRT prediction. When using Prosit is helpful for your research, please cite "Gessulat, Schmidt et al. 2019" DOI 10.1038/s41592-019-0426-7

https://www.proteomicsdb.org/prosit/

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Modifications in non-tryptic data #67

Closed kevinkovalchik closed 2 years ago

kevinkovalchik commented 3 years ago

Hello,

I am very interested in the non-tryptic model, but I am unsure of the modifications present in the training data. Is it the same as the tryptic data? i.e. CAM and ox(M)?

Thanks! Kevin

courcelm commented 2 years ago

I had the same question in mind. For MHC, it is not common to use carbamidomethylation. Is C treated as CAM in this model?

LLautenbacher commented 2 years ago

Yes, all our models are using carbamidomethylation as a fixed modification.