How to select the representative genes?

labxscut / CCNMF

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How to select the representative genes? #2

Open hfl112 opened 3 months ago

hfl112 commented 3 months ago

Hi Team CCNMF, I noticed only around 2k genes were used to run the CCNMF, is there any criteria that can use to get these gene lists or just randomly select genes on each chromosome?

Many thanks Fn

XQBai commented 1 month ago

Hi Fn,

As the preprocessing steps in NCI_N87_preprocess.R, the function "Iden_signal_segments()" will automatically identify the informative genes with high variance as used input for CCNMF.

Best, Xiangqi