search

lazear / sage

Proteomics search & quantification so fast that it feels like magic
https://sage-docs.vercel.app
MIT License
201 stars 38 forks source link

Segmentation fault (core dumped) #129

Closed colinliuzelin closed 2 months ago

colinliuzelin commented 2 months ago

Hi! I have a problem when using sage with a relative large search fasta file. I can succefully run the test example and other fasta database with less than 20000 sequences on my MS data. But when I run on large fasta file, the command give me the "Segmentation fault (core dumped)" without any other information. It could happen on both my local and HPC with 200 GB memory.

lazear commented 2 months ago

Sounds like you're out of memory!

You'll need to either use a computer with more RAM, reduce search space (less var mods, no semi-enzymatic), or reduce the size of your FASTA (e.g. search in multiple chunks and then recombine - see #97 for a mitigation)