Does it fit for 1kb to 2kb read length data

lbcb-sci / herro

HERRO is a highly-accurate, haplotype-aware, deep-learning tool for error correction of Nanopore R10.4.1 or R9.4.1 reads (read length of >= 10 kbps is recommended).

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Does it fit for 1kb to 2kb read length data #20

Open arpit20328 opened 7 months ago

arpit20328 commented 7 months ago

I am doing 16S rna amplicon based ONT sequencing.

My target region is only of 1kb to 2kb in length.

Per sample reads is around 50K.

Will HEERO give me good error filtered estimates ?

dominikstanojevic commented 7 months ago

Hello Arpit,

At the moment, HERRO does not work on short sequences. However, we may add support for them in the future.

ramiroricardo commented 5 months ago

Great... hoping you will!

yzhang-github-pub commented 4 months ago

@dominikstanojevic please do add support for shorter reads. There are a lot of applications where short reads in lower kb range are long enough. Thanks!

avilella commented 3 months ago

I am echoing the same request above: in my case, I would like to dorado correct single-cell RNAseq that are split in buckets containing the same barcode or barcode+UMI, which guarantees they should be sequencing the same original molecule.

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