HERRO is a highly-accurate, haplotype-aware, deep-learning tool for error correction of Nanopore R10.4.1 or R9.4.1 reads (read length of >= 10 kbps is recommended).
Hi,
I was wondering if it is possible to obtain summary stats on the number of heterozygous SNPs for HG002 sample using corrected reads and compare with PacBio HiFi or GIAB data against CHM13-T2T or GRCh38. This will indicate if there is overcorrection in favour of a single allele at a locus. I understand that you are preparing manuscript and this may be included in it. Awaiting results eagerly.
Cheers
Hi, I was wondering if it is possible to obtain summary stats on the number of heterozygous SNPs for HG002 sample using corrected reads and compare with PacBio HiFi or GIAB data against CHM13-T2T or GRCh38. This will indicate if there is overcorrection in favour of a single allele at a locus. I understand that you are preparing manuscript and this may be included in it. Awaiting results eagerly. Cheers