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legaultmarc / grstools

A bioinformatics framework for the construction and evaluation of genetic risk scores
https://legaultmarc.github.io/grstools/
MIT License
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Allow selection based on FDR q-value #8

Open legaultmarc opened 7 years ago

legaultmarc commented 7 years ago

Instead of using a p-value threshold, it would be nice to allow selection based on the FDR.

legaultmarc commented 7 years ago

Using this approach would require accounting for LD or clumping variants first.

legaultmarc commented 5 years ago

Actually an approach similar to what is used right now but that accumulates the p-values of the selected variants until FDR is reach would be pretty easy to do.