lehtiolab / ddamsproteomics

A Nextflow MS DDA proteomics pipeline
MIT License
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Make possible to accept correction matrix for isobaric quant #25

Open glormph opened 11 months ago

glormph commented 11 months ago

Isobaric quant from openMS can take a correction matrix or use default one. We currently only use default.

Isabelle has an idea that the "new" default that in openMS was introduced in version 2.5 or something, is worse for melt curve analysis. If we add an option for this we could change it and see how it turns out, as well as actually vary the matrix with different TMT batches.

glormph commented 10 months ago

According to Rui, this isnt very interesting, as the corrections are below noise level anyway, we'll stick with the default.