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leilaicruz / how-to-use-biological-high-throughput-data

The idea is to develop computational methods to process and use the already existing vast amount of genomic data , mainly focused in budding yeast
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Use of SGA data from Boone Lab [DRYGIN — Data Repository of Yeast Genetic INteractions](drygin.ccbr.utoronto.ca) #4

Open leilaicruz opened 4 years ago

leilaicruz commented 4 years ago

  1. How to benefit from this high throughput data set based on library of around a million of yeast double deletion mutants? Their fitness score is the colony size relative to WT (Pairwise interaction-format dataset 1)

  2. How to benefit from the dataset 2 where correlation matrix are drawn for all these gene interactions? (a dendogram of the .cdt data format can be viewed using Java TreeView)

leilaicruz commented 4 years ago

See some work in the repo called calculations-phd-bioinformatics