lgatto / synapter

Label-free data analysis pipeline for optimal identification and quantitation
https://lgatto.github.io/synapter/
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fm.fdr.nonunique seems not to work in synergise 2. Perhaps it does not override fm.minDelta? #128

Closed pavel-shliaha closed 7 years ago

pavel-shliaha commented 7 years ago

I have tried running synergise2 and for fragment matching I have specified fm.fdr.nonunique = 0.05. Note that I did not specify any argument for fm.minDelta, which defaults to 2. fm.fdr.nonunique and fm.fdr.unique should override fm.minDelta and fm.minCommon respectively

As a result when I run the pipeline with explicit commands I get that 0.05 fdr fm.fdr.nonunique should pick 1 as delta for non-unique fragments, but it does not seem to and even such clear non-unique fragments as:

image

are still rescue (I specify "rescue" behaviour for nonmatched merged EMRTs)

The code is in:

Y:\RAW\pvs22_QTOF_DATA_data3\synapter2paper\kuharev2015\bugs_investigation\NP_vs_S2

please have a look.