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lichen-lab / circMeta

A unified computational framework for genomic feature annotation and differential expression analysis of circular RNAs
https://github.com/lichen-lab/circMeta
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differential expressed circRNAs based on Circular-to-Linear Ratio (CLR) #5

Open Rumonnord opened 3 years ago

Rumonnord commented 3 years ago

Hello, I am using circMeta for differential expression analysis. Differential expressed circRNAs based on back-spliced junction reads worked with my data. However, I found error while doing differential expressed circRNAs based on Circular-to-Linear Ratio (CLR).

res2=circCLRDE(x1,n1,x2,n2,DE.method='wald',is.shrink=T)

estimate means...... Error in x1 + x2 : non-conformable arrays

In brief, I have two groups. One group has 5 replicate and another has 6.

Could you please let me know what could be the reason behind this error?

Thanks