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lima1 / PureCN

Copy number calling and variant classification using targeted short read sequencing
https://bioconductor.org/packages/devel/bioc/html/PureCN.html
Artistic License 2.0
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HRD score from PureCN outputs #352

Open ShvartsmanIrina opened 4 months ago

ShvartsmanIrina commented 4 months ago

Dear developers, can you recommend a tool or script for calculating HDR from PureCN outputs?

lima1 commented 4 months ago

Hi @ShvartsmanIrina, I never had a chance to look into this. See #159.

It would need some benchmarking. Any help appreciated.

See also https://ascopubs.org/doi/10.1200/GO.2023.9.Supplement_1.89 https://www.mdpi.com/2072-6694/15/13/3445.

ShvartsmanIrina commented 3 months ago

@lima1 , Thanks a lot! I'll try to translate the results into HRD score according to #159