Open GoogleCodeExporter opened 9 years ago
Original comment by alanruttenberg@gmail.com
on 4 Sep 2009 at 11:16
Issue from Melanie Courtot:
> 1.a. clinical phenotype
> definition reads "A clinically abnormal phenotype." which doesn't match the
> label and is circular.
Original comment by albertgo...@gmail.com
on 5 Jan 2010 at 7:13
Issue from Melanie Courtot:
> 1.b. disease phenotype
> definition reads "A clinically abnormal phenotype that is characteristic of
> a single disease." Per this definition it should be a subclass and not
> sibling of clinical phenotype.
Original comment by albertgo...@gmail.com
on 5 Jan 2010 at 7:14
'clinical phenotype' is still defined as "A clinically abnormal phenotype."
I think this definition is good.
The definition of 'disease phenotype' is "A clinically abnormal phenotype that
is characteristic of a single disease."
This definition is also good.
The problem is that disease phenotype is a sister class of clinical phenotype.
Based on the definitions of these classes, either disease phenotype should be
made a child of clinical phenotype or the definition of one or both classes
should be changed to make it clear that this proposed change would be
inappropriate.
Original comment by Alexande...@gmail.com
on 12 Jun 2012 at 3:25
Two concerns are being expressed: (a) whether the OGMS definition of
'phenotype' and its children is satisfactory (related is whether 'phenotype'
should be imported from or referenced to PATO); (b) given the current
definitions, logic dictates that 'disease phenotype' be a child of 'clinical
phenotype'.
Melanie's second comment (#3) and Alex's recent comment (#4) directly relate to
(b), which is also being discussed in this thread:
http://code.google.com/p/ogms/issues/detail?id=62
First, for clarity and to avoid duplication, I recommend these two threads be
combined, and one closed. Second, I recommend that 'disease phenotype' be made
a child of 'clinical phenotype' and discussion continue as to whether
definitions need to be changed.
-
Mark
Original comment by mpjens@gmail.com
on 12 Jun 2012 at 6:30
Original issue reported on code.google.com by
alanruttenberg@gmail.com
on 4 Sep 2009 at 11:14