Left handed mouse reverts to right handed after resuming from suspend

After resuming from suspend the left handed mouse reverts to right handed. If I navigate to the xfconf settings editor => pointers I can see that the checkbox RightHanded is not selected.

To get the mouse back to left handed mode I have to select RightHanded and then unselect Righthanded again via the settings editor. Other options to reset the mouse to left-handed mode are logout/login or a reboot of the system.

System Information:

System:    Kernel: 5.4.0-66-generic x86_64 bits: 64 compiler: gcc v: 9.3.0 Desktop: Xfce 4.14.2 
           tk: Gtk 3.24.13 wm: xfwm4 dm: LightDM Distro: Linux Mint 20.1 Ulyssa 
           base: Ubuntu 20.04 focal 
Machine:   Type: Desktop Mobo: Intel model: NUC6i5SYB v: H81131-502 serial: <filter> UEFI: Intel 
           v: SYSKLi35.86A.0073.2020.0909.1625 date: 09/09/2020 
CPU:       Topology: Dual Core model: Intel Core i5-6260U bits: 64 type: MT MCP arch: Skylake 
           rev: 3 L2 cache: 4096 KiB 
           flags: avx avx2 lm nx pae sse sse2 sse3 sse4_1 sse4_2 ssse3 vmx bogomips: 14400 
           Speed: 2701 MHz min/max: 400/2900 MHz Core speeds (MHz): 1: 2700 2: 2864 3: 2700 
           4: 2752 
Graphics:  Device-1: Intel Iris Graphics 540 driver: i915 v: kernel bus ID: 00:02.0 
           chip ID: 8086:1926 
           Display: x11 server: X.Org 1.20.9 driver: modesetting unloaded: fbdev,vesa 
           resolution: 3840x2160~60Hz 
           OpenGL: renderer: Mesa Intel Iris Graphics 540 (SKL GT3) v: 4.6 Mesa 20.2.6 
           direct render: Yes

Listing of the file ~/.config/xfce4/xfconf/xfce-perchannel-xml/pointers.xml:

<?xml version="1.0" encoding="UTF-8"?>

<channel name="pointers" version="1.0">
  <property name="Compx_24G_Receiver_Mouse" type="empty">
    <property name="RightHanded" type="bool" value="false"/>
    <property name="Threshold" type="int" value="1"/>
    <property name="Acceleration" type="double" value="5.000000"/>
  </property>
</channel>

Is there a way to change system wide default mouse settings? Any help is appreciated.

linuxmint / mintdesktop

Left handed mouse reverts to right handed after resuming from suspend #44