I´m wondering if there is a way to give idba a previous assembly from a subset of reads as a backbone/reference for an additional assembly of total reads. Would idba_hybrid provide such a functionality or is it only meant for whole reference genomes?
I´m searching something like the "--trusted-contigs" of spades, but spades uses too much computational resources.
I think can simply use your trusted-config with -l option. They will be used as long reads. You can also set maxk larger to make sure it uses the information in the trusted contigs.
Hi,
I´m wondering if there is a way to give idba a previous assembly from a subset of reads as a backbone/reference for an additional assembly of total reads. Would idba_hybrid provide such a functionality or is it only meant for whole reference genomes? I´m searching something like the "--trusted-contigs" of spades, but spades uses too much computational resources.
Best, Christ