Closed whui2bioinformatics closed 4 years ago
Hi, Thank you for your interest in the tool/paper! I will try my best to answer your questions here:
<condition>_mean_score
columns from the bindetect_results.txt
-file, which is the mean score across all sites. The scores are also z-score normalized per row, as some TFs naturally have higher mean scores than others (and this would influence the clustering).PlotAggregate
again to compare for the specific subset.I hope this answered your questions :-) Best Mette
Ok, thank you for your answer and advices. o( ̄︶ ̄)o
Hi, Mette. I'am interested in this picture showed in your paper. and I want to ask some questions about it. Thank you very much. The first question is what value you used to make heatmap shown in fig.a? the footprint mean score of all predicted sites of certain TF's or the mean score of bound sites of certain TF's? The second question is the footprint score filled in the these table,//beds/all.bed, //beds/ _bound.bed, /bindetect_results.{txt,xlsx}, normalized between conditions? Can we use the score to compare footprint among conditions, directly?
The last, I didn't find any differential footprint between conditions, just like this,
,
Could you give me some advices about this?
thanks again.