luoyunan / DTINet

A Network Integration Approach for Drug-Target Interaction Prediction
GNU General Public License v3.0
172 stars 60 forks source link

Prediction scores of drug–protein interactions #10

Closed ghost closed 4 years ago

ghost commented 5 years ago

Dear Yunan,

I was wondering what is the output of the DTINet. Is it only AUROC and AUPR? Can we have Prediction scores of drug–protein interactions (XZYT) as an output? Is it the mean Z-score following train_mf ?

Thanks a lot!

luoyunan commented 5 years ago

Yes. You can use the prediction score like this https://github.com/luoyunan/DTINet/blob/master/src/DTINet.m#L33

Note that although the variable is named as "Zscore", it is not the mean-centered average divided by the standard deviation. It's just a scalar score -- a higher score suggests it's more likely to be a DTI.

ghost commented 5 years ago

Thanks for your response. does the sign (+/-) show anything?

luoyunan commented 4 years ago

Sorry for the late response.

The sign does not have a particular meaning by definition.