m-jahn / genome-scale-models

Genome scale metabolic models in SBML format
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Reversibility of L-aspartate oxidase R_ASPO1 #9

Closed MJanasch closed 4 years ago

MJanasch commented 4 years ago

The reaction R_ASPO1 (1 M_h2o_c + 1 M_asp__L_c + 1 M_o2_c <=> 1 M_nh4_c + 1 M_oaa_c + 1 M_h2o2_c) is annotated as reversible in the model and can carry flux in the reverse direction. The reaction has a dG'0 of -92.4 kJ/mol (with NH3, Alberty, according to eQuilibrator), which can be assumed to render the reaction as irreversible, if no further thermodynamic analysis such as pytfa (https://github.com/EPFL-LCSB/pytfa) is applied.