malariagen / malariagen-data-python

Analyse MalariaGEN data from Python
https://malariagen.github.io/malariagen-data-python/latest/
MIT License
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explanation of site_annotations output #548

Open EricRLucas opened 1 month ago

EricRLucas commented 1 month ago

Please could the the docs include information on how to interpret the output of site_annotations()? I can't work out what the different levels of codon_nonsyn mean (effect?). I also can't quite work out what degeneracy shows (all 4-fold degenerate positions have a 0 score for nonsyn, which makes sense, but none of the other degeneracies have a 0; I would have thought that a 3-fold degenerate position would have a lot of 0 values).

leehart commented 1 month ago

Internal ref: https://github.com/malariagen/vector-ops/issues/1278