malariagen / pf-haploatlas

MIT License
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Ability to introduce phaseable heterozygous samples for analysis #2

Open Chiyun-Lee opened 5 months ago

Chiyun-Lee commented 5 months ago

Currently, heterozygous samples (containing more than one strain) are removed from analysis. Some samples can potentially be split into two new samples if they are "phaseable" into the two corresponding phases. Doing this would increase the number of samples available for overall analysis.

Chiyun-Lee commented 5 months ago

Notes for developers:

Backend: change code which currently excludes all het haplotypes (two+ strings separated by a comma) to identify which are phaseable/phased and keep them in df_clonal.

Frontend: implement option to include 1) just clonal haplotypes, 2) clonal + phaseable hets