In some cases, e.g., CRT C72S, there are different nucleotide differences that give the same amino acid. For example, Pf3D7_07_v3:403612 T->A is very common in Oceania, whereas Pf3D7_07_v3:403613 G->C is seen in South America, but both cause C72S. By allowing the user to select for nucleotide-level haplotypes, the app may offer a finer-grain level of control for tracking certain variants.
In some cases, e.g., CRT C72S, there are different nucleotide differences that give the same amino acid. For example, Pf3D7_07_v3:403612 T->A is very common in Oceania, whereas Pf3D7_07_v3:403613 G->C is seen in South America, but both cause C72S. By allowing the user to select for nucleotide-level haplotypes, the app may offer a finer-grain level of control for tracking certain variants.