Is high heterozygosity autotetraploid suitable?

marbl / merqury

k-mer based assembly evaluation

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Is high heterozygosity autotetraploid suitable? #108

Closed jia-wu-feng closed 11 months ago

jia-wu-feng commented 12 months ago

We assembled a highly heterozygous autotetraploid genome. And we got 4 haplotypes. I mixed the four haplotypes of this tetraploid and used this tool. I'm wondering if it's suitable to run the tool this way.

arangrhie commented 11 months ago

Hello @jia-wu-feng ,

You may need to extend the X axis to see the 4th peak on the spectra-cn plots. QV and phasing won't get affected by ploidy. Feel free to post your spectra-cn plots in case you need more help.

-Arang

jia-wu-feng commented 11 months ago

Thanks, Jia-Wu