Parsnp was designed to align the core genome of hundreds to thousands of bacterial genomes within a few minutes to few hours. Input can be both draft assemblies and finished genomes, and output includes variant (SNP) calls, core genome phylogeny and multi-alignments. Parsnp leverages contextual information provided by multi-alignments surrounding SNP sites for filtration/cleaning, in addition to existing tools for recombination detection/filtration and phylogenetic reconstruction.
According to the docs, parsnp.vcf is used to infer the phylogenetic tree. If so, then why does it contain the snps I want to filter out near recombination sites (-x option)? If REC and LCB snps are present in parsnp.vcf, how is parsnp.snps created?
According to the docs, parsnp.vcf is used to infer the phylogenetic tree. If so, then why does it contain the snps I want to filter out near recombination sites (-x option)? If REC and LCB snps are present in parsnp.vcf, how is parsnp.snps created?