The National Reference Center for Invasive Fungal Infections (NRZMyk) is the central contact point for diagnostics and management of invasive fungal infections.
S ≤ x and R ≥ y this is different then EUCAST where it is S ≤ x and R > y
This leads to samples being treated as susceptible or intermediate with CLSI breakpoints instead of resistant if the MIC value is at the upper boundary.
[ ] CLSI resistance is evaluated correctly
[ ] CLSI breakpoints are adapted ≤ 0.125 instead of 0.12
[ ] Existing data with invalid resistance is corrected
CLSI Breakpoints are defined with
S ≤ xandR ≥ ythis is different then EUCAST where it isS ≤ xandR > yThis leads to samples being treated as susceptible or intermediate with CLSI breakpoints instead of resistant if the MIC value is at the upper boundary.