SLOcatoR is an R package to annotate single-cell transcriptomes and open chromatin profiles from secondary lymphoid organs using the tonsil atlas as reference
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Using SingleCellExperiment's framework throughout the entire package #9
Refer to this as a way to handle the "switches":
https://github.com/MarcElosua/SPOTlight/blob/devel/R/runDeconvolution.R