Hello Mathew! Hope you're doing fine! I do neutrophil research and I'm a great fan of your SignacX, especially that other methods cannot identify of can only poorly identify neutrophils from scRNA-seq data!
My colleagues, who are studying other immune cells, are always using SingleR and I want to stop them, I mean convince them to use SignacX instead. So when I saw this benchmark study that SignacX accuracy is ~0.95 while SingleR is ~0.55, I wonder if you have data on PBMC as well.
Hello Mathew! Hope you're doing fine! I do neutrophil research and I'm a great fan of your SignacX, especially that other methods cannot identify of can only poorly identify neutrophils from scRNA-seq data!
Today, I found your benchmark analysis on synovial fluid data (https://cran.r-project.org/web/packages/SignacX/vignettes/signac-Seurat_AMP_RA.html) from Google. I just wonder if you have performed any benchmark study on PBMC data to calculate accuracy comparisons?
My colleagues, who are studying other immune cells, are always using SingleR and I want to stop them, I mean convince them to use SignacX instead. So when I saw this benchmark study that SignacX accuracy is ~0.95 while SingleR is ~0.55, I wonder if you have data on PBMC as well.
Thank you and warmest regards!