matthiaszeller / HBV

Genome-to-Genome Study of Hepatitis B Virus-infected individuals; EPFL, Fellay lab
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Checks.sina #3

Closed sinarueeger closed 5 years ago

sinarueeger commented 5 years ago

Hi @maousi,

For the sake of a Pull Request I made three tiny changes to your Jupyter Notebooks.

Here is a good paper on GWAS QC and the thresholds you can use: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001694/pdf/MPR-27-na.pdf

The viral PC's look a bit strange. Here are my first two PCs for comparison. I am using logisticPCA and a different imputation. Still weird that it looks so different. image