maxbiostat / R0_uncertainty

Some remarks on prior modelling for the basic reproductive number in the Susceptible-Infected-Recovered (SIR) epidemic model
6 stars 2 forks source link

Can we do a formal sensitivity analysis? #41

Open maxbiostat opened 2 years ago

maxbiostat commented 2 years ago

This paper proposes a way of formally assessing prior-data conflict and sensitivity. Might be a very nice plus once all of the building blocks are in place.

fccoelho commented 2 years ago

I am not sure of how efficient his method is if it still needs to use sampling methods to obtain the posterior.

For variance-based sensitivity, which is defined here, and simple inference models with closed form solutions, we can indeed save computations by computing the variance from the parameters of the posterior, and using that to calculate first order or higher order sensitivities.

Can't think of a non-trivial example, though...

maxbiostat commented 2 years ago

I am not sure of how efficient his method is if it still needs to use sampling methods to obtain the posterior.

I understand. But since we are going to use sampling methods (in Stan) to get the posterior, anyways, it might be worth a shot.

maxbiostat commented 2 years ago

Another nice paper to have a look: https://arxiv.org/pdf/2203.15184.pdf

maxbiostat commented 2 years ago

Yet another tool: https://corymccartan.github.io/adjustr/