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mbezaire / ca1

ca1 repository from 2017, linked to Open Source Brain
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Calcium concentration #10

Open mbezaire opened 7 years ago

mbezaire commented 7 years ago

eca defined in hoc then does not allow NEURON to recalculate eca based on cai and cao, so that different channels in same cell are operating from different calcium concentrations...

This is an issue in a neurogliaform and ivy cells.

Not such an issue in CCK and SCA...

This does change the behavior of neurogliaform cells and ivy cells...

mbezaire commented 7 years ago

Version 1.0 - version that runs the code corresponding to what was published in eLife.

Version 2.0 - most recent (would have updated NeuroML and NEURON that correspond and that have addressed calcium confusion in NGF/Ivy cells)

mbezaire commented 7 years ago

1 more question about these 4 cells: In CCK and SCA eca is set to ecaval (and kept constant), while in Ivy and NGF ecaval is calculated, but not used, thus NEURON keeps updating eca. Was this the purpose or is it a bug? (eca is used by ch_CavN)

andrisecker commented 7 years ago

I just double checked this and NEURON does update eca after setting from hoc level - that one is used only as an initial value. So there is no bug, it's just a bit inconsistent between CCK, SCA & Ivy, NGF. Sorry for the inconvenience.