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mccoy-lab / hgv_modules

Teaching modules for Human Genome Variation Lab.
https://mccoy-lab.github.io/hgv_modules/
Creative Commons Attribution 4.0 International
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Detail: viruses, including SARS-CoV-2, do in fact recombine #6

Closed jshoyer closed 1 year ago

jshoyer commented 1 year ago

https://github.com/mccoy-lab/hgv_modules/blob/e4e336e66a49202549b2641143dc90a32b86257b/11-coronavirus/11-coronavirus.Rmd#L31

A quick search will show many excellent review articles on virus recombination and reassortment. The confusion may be related to the fact that viruses do not have meiosis.

All Pango lineages of SARS-CoV-2 that start with the letter ‘X’, including XBB.1.5, are high-confidence recombinants.

The point about how recombination complicates phylogenetic analysis is important. If students are interested in this I would recommend the following pdf slides and accompanying tutorial on detecting recombination: https://davidrasm.github.io/MolEpi/lectures/MolEpi.Recombination.2022.Lecture6.pdf

stephaniemyan commented 1 year ago

Thanks for the suggestion! I've edited the paragraph you referenced to discuss viral recombination. Thanks as well for linking these recombination slides.