anvi'o uses DIAMOND in many cool functionalities, and offers selection of fast and sensitive modes. According to the recent publication on the updated version of DIAMOND (https://www.nature.com/articles/s41592-021-01101-x) its sensitive mode in the newer versions is substantially better than it is in older versions. There are also two additional sensitivity modes added (very and ultra).
The solution
Add additional sensitivity modes to relevant programs, and check compatibility of recent DIAMOND versions with other dependencies. I suspect you're already working on this, but couldn't find an open issue about it.
Beneficiaries
most anvi'o users, as DIAMOND is used in a range of anvio functinalities
The need
anvi'o uses DIAMOND in many cool functionalities, and offers selection of fast and sensitive modes. According to the recent publication on the updated version of DIAMOND (https://www.nature.com/articles/s41592-021-01101-x) its sensitive mode in the newer versions is substantially better than it is in older versions. There are also two additional sensitivity modes added (very and ultra).
The solution
Add additional sensitivity modes to relevant programs, and check compatibility of recent DIAMOND versions with other dependencies. I suspect you're already working on this, but couldn't find an open issue about it.
Beneficiaries
most anvi'o users, as DIAMOND is used in a range of anvio functinalities